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DecodeMyBio vs CircadiaOS

A side-by-side comparison built from both listings. Blank cells mean the company has not given that detail; we never guess.

DecodeMyBio compared with CircadiaOS
DetailDecodeMyBio logo DecodeMyBioCircadiaOS logo CircadiaOS
What it doesPharmacogenomic analysis from your existing DNA data The thermostat schedule that learns from your sleep
StageStartup Not given
Founded2025 Not given
Based inLT US
Pricing modelFreemium Freemium
PricingFree to start with genome overview. Decode: $19.99 one-time for lifetime access to all medication results. Decode Complete (includes Medication Response Profile PDF): $29.99 one-time or $10 if you already have Decode. Free: starting temperature schedule, optional wearable connection, nightly sleep data and trends, no thermostat control. Premium (monthly): $12.99/month with automatic thermostat control, four-phase schedule, 14-night starting period, one-variable-at-a-time adjustment from wearable data, 14-day free
Key features
  • Upload raw DNA data from 23andMe, AncestryDNA, MyHeritage, FamilyTreeDNA, Living DNA or VCF files
  • CPIC-based drug-gene guidance with metabolizer phenotypes
  • Medication Response Profile PDF for prescribers
  • Carrier status reporting from your variants
  • Transparent sourcing with variant-level citations
  • Four-phase overnight temperature schedule (pre-sleep, early night, late night, pre-wake)
  • One-variable-at-a-time personalization held for 7 to 14 nights per change
  • Wearable integration: Apple Watch, Oura Ring, Whoop, Garmin, Fitbit
  • Thermostat compatibility with Nest, ecobee, Honeywell Home and 20+ brands
  • 14-night starting period and reference point on Premium
  • User-set temperature floor and ceiling, never below 63°F
  • Why This Curve display showing where each setpoint came from and data behind it
  • Best vs Worst nights comparison showing highest and lowest scoring nights
  • Manual override capability with automatic resumption next night
  • Referral program earning free months of Premium for every three friends who join
What makes it different
  • No new test required—analyzes raw data you already have from 23andMe or AncestryDNA
  • Reports what your file cannot answer rather than guessing
  • No new hardware required—works with your existing smart thermostat and wearable
  • Software-first approach running sleep algorithms on your thermostat rather than requiring specialized cooling beds
  • Personalization through one-change-at-a-time adjustments graded against your own sleep data
  • Complete transparency showing where every setpoint comes from and how much data supports it
Community votes00
DR (Domain Rating by Ahrefs)3 +1 (up) since last check13 no change since last check
Trust Flow (Majestic)44
Citation Flow (Majestic)1924
Referring domains (Majestic)1147

6 details filled in for both companies.

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